Recent studies of unconventional superconductivity have focused on charge or spin fluctuation, instead of electron-phonon coupling, as an origin of attractive interaction between electrons. On the other hand, a multipole order, which represents electrons degrees of freedom in strongly correlated and spin-orbit-coupled systems, has recently been attracting much attention. Stimulated by this background, we investigate multipole-fluctuation-mediated superconductivity, which proposes a new pairing mechanism of unconventional superconductivity. Indeed, previous works have shown spin-triplet superconductivity induced by fluctuations of odd-parity electric multipole orders in isotropic systems. In this study, we establish a general formulation of the multipole-fluctuation-mediated superconductivity for all multipole symmetries, in both isotropic and crystalline systems. As a result, we reveal various anisotropic pairings induced by odd-parity and/or higher-order multipole fluctuations, which are beyond the ordinary charge or spin fluctuations. Topological superconductivity due to the mechanism is also discussed. Based on the obtained results, we discuss unconventional superconductivity in doped SrTiO$_3$, PrTi$_2$Al$_{20}$, Li$_2$(Pd, Pt)$_3$B, and magnetic multipole metals.