In this paper, we investigate the phase sensitivities in two-path optical interferometry with asymmetric beam splitters. Here, we present the optimal conditions for the transmission ratio and the phase of the beam splitter to gain the highest sensitivities for a general class of non-classical states with parity symmetry. Additionally, we address the controversial question of whether the scheme with a combination of coherent state and photon-added or photon-subtracted squeezed vacuum state is better or worse than the most celebrated one using a combination of coherent state and squeezed vacuum state.