The usability and practicality of any machine learning (ML) applications are largely influenced by two critical but hard-to-attain factors: low latency and low cost. Unfortunately, achieving low latency and low cost is very challenging when ML depends on real-world data that are highly distributed and rapidly growing (e.g., data collected by mobile phones and video cameras all over the world). Such real-world data pose many challenges in communication and computation. For example, when training data are distributed across data centers that span multiple continents, communication among data centers can easily overwhelm the limited wide-area network bandwidth, leading to prohibitively high latency and high cost. In this dissertation, we demonstrate that the latency and cost of ML on highly-distributed and rapidly-growing data can be improved by one to two orders of magnitude by designing ML systems that exploit the characteristics of ML algorithms, ML model structures, and ML training/serving data. We support this thesis statement with three contributions. First, we design a system that provides both low-latency and low-cost ML serving (inferencing) over large-scale and continuously-growing datasets, such as videos. Second, we build a system that makes ML training over geo-distributed datasets as fast as training within a single data center. Third, we present a first detailed study and a system-level solution on a fundamental and largely overlooked problem: ML training over non-IID (i.e., not independent and identically distributed) data partitions (e.g., facial images collected by cameras varies according to the demographics of each cameras location).
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