Measurements of the post-reionization 21-cm bispectrum $B_{{rm HI}}(mathbf{k_1},mathbf{k_2},mathbf{k_3})$ using various upcoming intensity mapping experiments hold the potential for determining the cosmological parameters at a high level of precision. In this paper we have estimated the 21-cm bispectrum in the $z$ range $1 le z le 6$ using semi-numerical simulations of the neutral hydrogen (${rm HI}$) distribution. We determine the $k$ and $z$ range where the 21-cm bispectrum can be adequately modelled using the predictions of second order perturbation theory, and we use this to predict the redshift evolution of the linear and quadratic ${rm HI}$ bias parameters $b_1$ and $b_2$ respectively. The $b_1$ values are found to decreases nearly linearly with decreasing $z$, and are in good agreement with earlier predictions obtained by modelling the 21-cm power spectrum $P_{{rm HI}}(k)$. The $b_2$ values fall sharply with decreasing $z$, becomes zero at $z sim 3$ and attains a nearly constant value $b_2 approx - 0.36$ at $z<2$. We provide polynomial fitting formulas for $b_1$ and $b_2$ as functions of $z$. The modelling presented here is expected to be useful in future efforts to determine cosmological parameters and constrain primordial non-Gaussianity using the 21-cm bispectrum.
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