The Giant Pairing Vibration, a two-nucleon collective mode originating from the second shell above the Fermi surface, has long been predicted and expected to be strongly populated in two-nucleon transfer reactions with cross sections similar to those of the normal Pairing Vibration. Recent experiments have provided evidence for this mode in $^{14,15}$C but, despite sensitive studies, it has not been definitively identified either in Sn or Pb nuclei where pairing correlations are known to play a crucial role near their ground states. In this paper we review the basic theoretical concepts of this elusive state and the status of experimental searches in heavy nuclei. We discuss the hindrance effects due to Q-value mismatch and the use of weakly-bound projectiles as a way to overcome the limitations of the (p,t) and (t,p) reactions. We also discuss the role of the continuum and conclude with some possible future developments.