We compute radiative corrections to nuclear reaction rates that determine the outcome of the Big-Bang Nucleosynthesis (BBN). Any nuclear reaction producing a photon with an energy above $2m_e$ must be supplemented by the corresponding reaction where the final state photon is replaced by an electron-positron pair. We find that pair production brings a typical $0.2 %$ enhancement to photon emission rates, resulting in a similar size corrections to elemental abundances. The exception is $^4{rm He}$ abundance, which is insensitive to the small changes in the nuclear reaction rates. We also investigate the effect of vacuum polarisation on the Coulomb barrier, which brings a small extra correction when reaction rates are extrapolated from the measured energies to the BBN Gamow peak energies.