We report on lattice QCD calculations of the nucleon isovector axial, scalar, and tensor charges. Our calculations are performed on two 2+1-flavor ensembles generated using a 2-HEX-smeared Wilson-clover action at the physical pion mass and lattice spacings $aapprox$ 0.116 and 0.093 fm. We use a wide range of source-sink separations - eight values ranging from roughly 0.4 to 1.4 fm on the coarse ensemble and three values from 0.9 to 1.5 fm on the fine ensemble - which allows us to perform an extensive study of excited-state effects using different analysis and fit strategies. To determine the renormalization factors, we use the nonperturbative Rome-Southampton approach and compare RI-MOM and RI-SMOM intermediate schemes to estimate the systematic uncertainties. Our final results are computed in the MS-bar scheme at scale 2 GeV. The tensor and axial charges have uncertainties of roughly 4%, $g_T=0.972(41)$ and $g_A=1.265(49)$. The resulting scalar charge, $g_S=0.927(303)$, has a much larger uncertainty due to a stronger dependence on the choice of intermediate renormalization scheme and on the lattice spacing.
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