It is a honor to write a contribution on this memorial for Sandro Massidda. For both of us, at different stages of our life, Sandro was first and foremost a friend. We both admired his humble, playful and profound approach to life and physics. In this contribution we describe the route which permitted to meet a long-standing challenge in solid state physics, i.e. room temperature superconductivity. In less than 20 years the Tc of conventional superconductors, which in the last century had been widely believed to be limited to 25 K, was raised from 40 K in MgB2 to 265 K in LaH10. This discovery was enabled by the development and application of computational methods for superconductors, a field in which Sandro Massidda played a major role.
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