We demonstrate that the multi-top productions efficiently probe the CP-property of top-Higgs interaction and the Higgs-boson width at the LHC. The four top-quark production alone can exclude a purely CP-odd top-quark Yukawa coupling at the 13~TeV LHC with an integrated luminosity of $430~{rm fb}^{-1}$, regardless the size of the Yukawa coupling. Combining the single Higgs-boson production, the $tbar{t}H$ associated production and the four top-quark production, we show that the CP-phase of the top-quark Yukawa coupling and the Higgs-boson width can be stringently bounded at the LHC with integrated luminosities of $300~{rm fb}^{-1}$ and $3000~{rm fb}^{-1}$.