We prove sharp blow up rates of solutions of higher order conformally invariant equations in a bounded domain with an isolated singularity, and show the asymptotic radial symmetry of the solutions near the singularity. This is an extension of the celebrated theorem of Caffarelli-Gidas-Spruck for the second order Yamabe equation with isolated singularities to higher order equations. Our approach uses blow up analysis for local integral equations, and is unified for all critical elliptic equations of order smaller than the dimension. We also prove the existence of Fowler solutions to the global equations, and establish a sup*inf type Harnack inequality of Schoen for integral equations.
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