Let $ngeq 3$, $0< m<frac{n-2}{n}$ and $T>0$. We construct positive solutions to the fast diffusion equation $u_t=Delta u^m$ in $mathbb{R}^ntimes(0,T)$, which vanish at time $T$. By introducing a scaling parameter $beta$ inspired by cite{DKS}, we study the second-order asymptotics of the self-similar solutions associated with $beta$ at spatial infinity. We also investigate the asymptotic behavior of the solutions to the fast diffusion equation near the vanishing time $T$, provided that the initial value of the solution is close to the initial value of some self-similar solution and satisfies some proper decay condition at infinity. Depending on the range of the parameter $beta$, we prove that the rescaled solution converges either to a self-similar profile or to zero as $t earrow T$. The former implies asymptotic stabilization towards a self-similar solution, and the latter is a new vanishing phenomenon even for the case $nge3$ and $m=frac{n-2}{n+2},$ which corresponds to the Yamabe flow on $mathbb{R}^n$ with metric $g=u^{frac{4}{n+2}}dx^2$.