In blind quantum computation (BQC), a client delegates her quantum computation to a server with universal quantum computers who learns nothing about the clients private information. In measurement-based BQC model, entangled states are generally used to realize quantum computing. However, to generate a large-scale entangled state in experiment becomes a challenge issue. In circuit-based BQC model, single-qubit gates can be realized precisely, but entangled gates are probabilistically successful. This remains a challenge to realize entangled gates with a deterministic method in some systems. To solve above two problems, we propose the first hybrid universal BQC protocol based on measurements and circuits, where the client prepares single-qubit states and the server performs universal quantum computing. We analyze and prove the correctness, blindness and verifiability of the proposed protocol.