Using hydrodynamical simulations of entire galactic discs similar to the Milky Way, reaching 4.6pc resolution, we study the origins of observed physical properties of giant molecular clouds (GMCs). We find that efficient stellar feedback is a necessary ingredient in order to develop a realistic interstellar medium (ISM), leading to molecular cloud masses, sizes, velocity dispersions and virial parameters in excellent agreement with Milky Way observations. GMC scaling relations observed in the Milky Way, such as the mass-size ($M$--$R$), velocity dispersion-size ($sigma$--$R$), and the $sigma$--$RSigma$ relations, are reproduced in a feedback driven ISM when observed in projection, with $Mpropto R^{2.3}$ and $sigmapropto R^{0.56}$. When analysed in 3D, GMC scaling relations steepen significantly, indicating potential limitations of our understanding of molecular cloud 3D structure from observations. Furthermore, we demonstrate how a GMC populations underlying distribution of virial parameters can strongly influence the scatter in derived scaling relations. Finally, we show that GMCs with nearly identical global properties exist in different evolutionary stages, where a majority of clouds being either gravitationally bound or expanding, but with a significant fraction being compressed by external ISM pressure, at all times.
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