Motivation: Automatically testing changes to code is an essential feature of continuous integration. For open-source code, without licensed dependencies, a variety of continuous integration services exist. The COnstraint-Based Reconstruction and Analysis (COBRA) Toolbox is a suite of open-source code for computational modelling with dependencies on licensed software. A novel automated framework of continuous integration in a semi-licensed environment is required for the development of the COBRA Toolbox and related tools of the COBRA community. Results: ARTENOLIS is a general-purpose infrastructure software application that implements continuous integration for open-source software with licensed dependencies. It uses a master-slave framework, tests code on multiple operating systems, and multip
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