ROXs 12 (2MASS J16262803-2526477) is a young star hosting a directly imaged companion near the deuterium-burning limit. We present a suite of spectroscopic, imaging, and time-series observations to characterize the physical and environmental properties of this system. Moderate-resolution near-infrared spectroscopy of ROXs 12 B from Gemini-North/NIFS and Keck/OSIRIS reveals signatures of low surface gravity including weak alkali absorption lines and a triangular $H$-band pseudo-continuum shape. No signs of Pa$beta$ emission are evident. As a population, however, we find that about half (46 $pm$ 14%) of young ($lesssim$15 Myr) companions with masses $lesssim$20 $M_mathrm{Jup}$ possess actively accreting subdisks detected via Pa$beta$ line emission, which represents a lower limit on the prevalence of circumplanetary disks in general as some are expected to be in a quiescent phase of accretion. The bolometric luminosity of the companion and age of the host star (6$^{+4}_{-2}$ Myr) imply a mass of 17.5 $pm$ 1.5 $M_mathrm{Jup}$ for ROXs 12 B based on hot-start evolutionary models. We identify a wide (5100 AU) tertiary companion to this system, 2MASS J16262774-2527247, which is heavily accreting and exhibits stochastic variability in its $K2$ light curve. By combining $v$sin$i_*$ measurements with rotation periods from $K2$, we constrain the line-of-sight inclinations of ROXs 12 A and 2MASS J16262774-2527247 and find that they are misaligned by 60$^{+7}_{-11}$$^{circ}$. In addition, the orbital axis of ROXs 12 B is likely misaligned from the spin axis of its host star ROXs 12 A, suggesting that ROXs 12 B formed akin to fragmenting binary stars or in an equatorial disk that was torqued by the wide stellar tertiary.
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