Modeling the complex interactions between users and items as well as amongst items themselves is at the core of designing successful recommender systems. One classical setting is predicting users personalized sequential behavior (or `next-item recommendation), where the challenges mainly lie in modeling `third-order interactions between a user, her previously visited item(s), and the next item to consume. Existing methods typically decompose these higher-order interactions into a combination of pairwise relationships, by way of which user preferences (user-item interactions) and sequential patterns (item-item interactions) are captured by separate components. In this paper, we propose a unified method, TransRec, to model such third-order relationships for large-scale sequential prediction. Methodologically, we embed items into a `transition space where users are modeled as translation vectors operating on item sequences. Empirically, this approach outperforms the state-of-the-art on a wide spectrum of real-world datasets. Data and code are available at https://sites.google.com/a/eng.ucsd.edu/ruining-he/.