We present a selection of the first results obtained in a comprehensive calculation of ground state properties of even-even superheavy nuclei in the region of 96 < Z < 136 and 118 < N < 320 from the Quark-Meson-Coupling model (QMC). Ground state binding energies, the neutron and proton number dependence of quadrupole deformations and Q$_alpha$ values are reported for even-even nuclei with 100 < Z < 136 and compared with available experimental data and predictions of macro-microscopic models. Predictions of properties of nuclei, including Q$_alpha$ values, relevant for planning future experiments are presented.
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