We present lattice QCD results of baryon-baryon potentials in S=-3 sector, i.e., XiSigma (I=3/2) potentials and XiLambda-XiSigma coupled channel potentials (I=1/2) by using the 2+1 flavor gauge configurations with almost the physical quark masses generated on 96^4 lattice with 1/a simeq 2.3 GeV and L = 96a simeq 8.1 fm where m_pi simeq 146 MeV and m_K simeq 525 MeV. These potentials are obtained based on the time-dependent HAL QCD method with a non-relativistic approximation. Qualitative behaviors of the results are found to be consistent with those in the flavor SU(3) limit.
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