We study the dynamics of a localized spin-1/2 driven by a time-periodic magnetic field that undergoes a topological transition. Despite the strongly non-adiabatic effects dominating the spin dynamics, we find that the fields topology appears clearly imprinted in the Floquet spin states through an effective Berry phase emerging in the quasienergy. This has remarkable consequences on the spin resonance condition suggesting a whole new class of experiments to spot topological transitions in the dynamics of spins and other two-level systems, from nuclear magnetic resonance to strongly-driven superconducting qubits.