In this paper I have given a mathematical model of Cell reprogramming from a different contexts. Here I considered there is a delay in differential regulator rate equations due to intermediate regulators regulations. At first I gave some basic mathematical models by Ferell Jr.[2] of reprogramming and after that I gave mathematical model of cell reprogramming by Mithun Mitra[4]. In the last section I contributed a mathematical model of cell reprogramming from intermediate steps regulations and tried to find the critical point of pluripotent cell.