We report on a set of long-term general-relativistic three-dimensional (3D) multi-group (energy-dependent) neutrino-radiation hydrodynamics simulations of core-collapse supernovae. We employ a full 3D two-moment scheme with the local M1 closure, three neutrino species, and 12 energy groups per species. With this, we follow the post-core-bounce evolution of the core of a nonrotating $27$-$M_odot$ progenitor in full unconstrained 3D and in octant symmetry for $gtrsim$$ 380,mathrm{ms}$. We find the development of an asymmetric runaway explosion in our unconstrained simulation. We test the resolution dependence of our results and, in agreement with previous work, find that low resolution artificially aids explosion and leads to an earlier runaway expansion of the shock. At low resolution, the octant and full 3D dynamics are qualitatively very similar, but at high resolution, only the full 3D simulation exhibits the onset of explosion.