A matching $M$ in a graph $G$ is said to be uniquely restricted if there is no other matching in $G$ that matches the same set of vertices as $M$. We describe a polynomial-time algorithm to compute a maximum cardinality uniquely restricted matching in an interval graph, thereby answering a question of Golumbic et al. (Uniquely restricted matchings, M. C. Golumbic, T. Hirst and M. Lewenstein, Algorithmica, 31:139--154, 2001). Our algorithm actually solves the more general problem of computing a maximum cardinality strong independent set in an interval nest digraph, which may be of independent interest. Further, we give linear-time algorithms for computing maximum cardinality uniquely restricted matchings in proper interval graphs and bipartite permutation graphs.