We present the results of a search for WIMPs from the commissioning run of the PandaX-II experiment located at the China Jinping underground Laboratory. A WIMP search data set with an exposure of 306$times$19.1 kg-day was taken, while its dominant $^{85}$Kr background was used as the electron recoil calibration. No WIMP candidates are identified, and a 90% upper limit is set on the spin-independent elastic WIMP-nucleon cross section with a lowest excluded cross section of 2.97$times$10$^{-45}$~cm$^2$ at a WIMP mass of 44.7~GeV/c$^2$.
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