We study the local indistinguishability of mutually orthogonal product basis quantum states in the high-dimensional quantum system. In the quantum system of $mathbb{C}^dotimesmathbb{C}^d$, where $d$ is odd, Zhang emph{et al} have constructed $d^2$ orthogonal product basis quantum states which are locally indistinguishable in [Phys. Rev. A. {bf 90}, 022313(2014)]. We find a subset contains with $6d-9$ orthogonal product states which are still locally indistinguishable. Then we generalize our method to arbitrary bipartite quantum system $mathbb{C}^motimesmathbb{C}^n$. We present a small set with only $3(m+n)-9$ orthogonal product states and prove these states are LOCC indistinguishable. Even though these $3(m+n)-9$ product states are LOCC indistinguishable, they can be distinguished by separable measurements. This shows that separable operations are strictly stronger than the local operations and classical communication.
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