Modified Newtonian dynamics (MOND) is an empirical theory originally proposed to explain the rotation curves of spiral galaxies by modifying the gravitational acceleration, rather than by invoking dark matter. Here,we set constraints on MOND using an up-to-date compilation of kinematic tracers of the Milky Way and a comprehensive collection of morphologies of the baryonic component in the Galaxy. In particular, we find that the so-called standard interpolating function cannot explain at the same time the rotation curve of the Milky Way and that of external galaxies for any of the baryonic models studied, while the so-called simple interpolating function can for a subset of models. Upcoming astronomical observations will refine our knowledge on the morphology of baryons and will ultimately confirm or rule out the validity of MOND in the Milky Way. We also present constraints on MOND-like theories without making any assumptions on the interpolating function.