We compare the predictions of three independently developed semi-analytic galaxy formation models that are being used to aid in the interpretation of results from the CANDELS survey. These models are each applied to the same set of halo merger trees extracted from the Bolshoi simulation and are carefully tuned to match the local galaxy stellar mass function using the powerful method of Bayesian Inference coupled with MCMC or by hand. The comparisons reveal that in spite of the significantly different parameterizations for star formation and feedback processes, the three models yield qualitatively similar predictions for the assembly histories of galaxy stellar mass and star formation over cosmic time. We show that the SAMs generally require strong outflows to suppress star formation in low-mass halos to match the present day stellar mass function. However, all of the models considered produce predictions for the star formation rates and metallicities of low-mass galaxies that are inconsistent with existing data and diverge between the models. We suggest that large differences in the metallicity relations and small differences in the stellar mass assembly histories of model galaxies stem from different assumptions for the outflow mass-loading factor. Importantly, while more accurate observational measurements for stellar mass, SFR and metallicity of galaxies at 1<z<5 will discriminate between models, the discrepancies between the models and existing data of these observables have already revealed challenging problems in understanding star formation and its feedback in galaxy formation. The three sets of models are being used to construct catalogs of mock galaxies on light cones that have the same geometry as the CANDELS survey, which should be particularly useful for quantifying the biases and uncertainties on measurements and inferences from the real observations. -ABRIDGED
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