We investigate the radial distribution of the low-mass X-ray binary (LMXB) population in the elliptical galaxy NGC 4649, using Chandra and Hubble data to separate the field and globular cluster (GC) populations. GCs with LMXBs have the same radial distribution as the parent red and blue GCs. The radial profile of field LMXBs follows the V-band profile within the D25 of NGC 4649. Using the spatial information provided by our data, we find that the global galaxy-wide relations between cumulative number and luminosity of LMXBs and the integrated stellar mass hold on local scales within D25. An excess of field LMXBs with respect to the V-light is observed in the galaxys outskirt, which may be partially due to unidentified GC sources or to a rejuvenated field LMXB population caused by past merging interactions.