The production of B+- mesons in proton-proton collisions at sqrt(s)=7 TeV is studied using 35 pb-1 of data collected by the LHCb detector. The B+- mesons are reconstructed exclusively in the B+- -> J/psi K+- mode, with J/psi -> mu+ mu-. The differential production cross-section is measured as a function of the B+- transverse momentum in the fiducial region 0 < pT < 40 GeV/c and with rapidity 2.0 < y < 4.5. The total cross-section, summing up B+ and B-, is measured to be sigma(pp -> B+- X, 0 < pT < 40 GeV/c, 2.0 < y < 4.5) = 41.4 +- 1.5 (stat.) +- 3.1 (syst.) mub.
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