Current theories of the origin of the Universe, including string theory, predict the existence of a multiverse containing many bubble universes. These bubble universes will generically collide, and collisions with ours produce cosmic wakes that enter our Hubble volume, appear as unusually symmetric disks in the cosmic microwave background (CMB) and disturb large scale structure (LSS). There is preliminary observational evidence consistent with one or more of these disturbances on our sky. However, other sources can produce similar features in the CMB temperature map and so additional signals are needed to verify their extra-universal origin. Here we find, for the first time, the detailed three-dimensional shape and CMB temperature and polarization signals of the cosmic wake of a bubble collision in the early universe consistent with current observations. The predicted polarization pattern has distinctive features that when correlated with the corresponding temperature pattern are a unique and striking signal of a bubble collision. These features represent the first verifiable prediction of the multiverse paradigm and might be detected by current experiments such as Planck and future CMB polarization missions. A detection of a bubble collision would confirm the existence of the Multiverse, provide compelling evidence for the string theory landscape, and sharpen our picture of the Universe and its origins.