We compute net-proton probability distributions in heavy ion collisions within the hadron resonance gas model. The model results are compared with data taken by the STAR Collaboration in Au-Au collisions at sqrt(s_{NN})= 200 GeV for different centralities. We show that in peripheral Au-Au collisions the measured distributions, and the resulting first four moments of net-proton fluctuations, are consistent with results obtained from the hadron resonance gas model. However, data taken in central Au-Au collisions differ from the predictions of the model. The observed deviations can not be attributed to uncertainties in model parameters. We discuss possible interpretations of the observed deviations.
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