The self-consistent random phase approximation (RPA) approach with the residual interaction derived from a relativistic point-coupling energy functional is applied to evaluate the isospin symmetry-breaking corrections {delta}c for the 0+to0+ superallowed Fermi transitions. With these {delta}c values, together with the available experimental ft values and the improved radiative corrections, the unitarity of the Cabibbo-Kobayashi-Maskawa (CKM) matrix is examined. Even with the consideration of uncertainty, the sum of squared top-row elements has been shown to deviate from the unitarity condition by 0.1% for all the employed relativistic energy functionals.