We investigate the validity of the generalized second law (GSL) of gravitational thermodynamics in a non-flat FRW universe containing the interacting generalized Chaplygin gas with the baryonic matter. The dynamical apparent horizon is assumed to be the boundary of the universe. We show that for the interacting generalized Chaplygin gas as a unified candidate for dark matter (DM) and dark energy (DE), the equation of state parameter can cross the phantom divide. We also present that for the selected model under thermal equilibrium with the Hawking radiation, the GSL is always satisfied throughout the history of the universe for any spatial curvature, independently of the equation of state of the interacting generalized Chaplygin gas model.
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