We summarize several projects carried out by the CTEQ global analysis of parton distribution functions (PDFs) of the proton during 2010. We discuss a recently released CT10 family of PDFs with a fixed and variable QCD coupling strength; implementation of combined HERA and Tevatron lepton asymmetry data sets; theoretical issues associated with the analysis of $W$ charge asymmetry in PDF fits; PDFs for leading-order shower programs; and constraints on new color-octet fermions from the hadronic data.
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