Criteria suitable for measuring entanglement between two different potential wells in a Bose- Einstein condensation (BEC) are evaluated. We show how to generate the required entanglement, utilizing either an adiabatic two-mode or dynamic four-mode interaction strategy, with techniques that take advantage of s-wave scattering interactions to provide the nonlinear coupling. The dynamic entanglement method results in an entanglement signature with spatially separated detectors, as in the Einstein-Podolsky-Rosen (EPR) paradox.