A quark interaction with topologically nontrivial gluonic fields, instantons and sphalerons, violates P~ and CP~ symmetry. In the strong magnetic field of a noncentral nuclear collision such interactions lead to the charge separation along the magnetic field, the so-called chiral magnetic effect (CME). Recent results from the STAR collaboration on charge dependent correlations are consistent with theoretical expectations for CME but may have contributions from other effects, which prevents definitive interpretation of the data. Here I propose to use central body-body $U+U$ collisions to disentangle correlations due to CME from possible background correlations due to elliptic flow. Further more quantitative studies can be performed with collision of isobaric beams.
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