Differential measurements of the elliptic (v_2) and hexadecapole (v_4) Fourier flow coefficients are reported for charged hadrons as a function of transverse momentum (p_T) and collision centrality or the number of participant nucleons (N_part) for Au+Au collisions at sqrt(s_NN)=200 GeV. The v_{2,4} measurements at pseudorapidity |eta|<=0.35 obtained with four separate reaction plane detectors positioned in the range 1.0<|eta|<3.9 show good agreement, indicating the absence of significant eta-dependent nonflow perturbations. Sizable values for v_4(p_T) are observed with a ratio v_4(p_T,N_part)/v_2^2(p_T,N_part)~0.8 for 50<N_part<200, which is compatible with the combined effects of a finite viscosity and initial eccentricity fluctuations. For N_part>200 this ratio increases up to 1.7 in the most central collisions.