Nuclear collisions recreate conditions in the universe microseconds after the Big Bang. Only a very small fraction of the emitted fragments are light nuclei, but these states are of fundamental interest. We report the observation of antihypertritons - composed of an antiproton, antineutron, and antilambda hyperon - produced by colliding gold nuclei at high energy. Our analysis yields 70 +- 17 antihypertritons and 157 +- 30 hypertritons. The measured yields of hypertriton (antihypertriton) and helium3 (antihelium3) are similar, suggesting an equilibrium in coordinate and momentum space populations of up, down, and strange quarks and antiquarks, unlike the pattern observed at lower collision energies. The production and properties of antinuclei, and nuclei containing strange quarks, have implications spanning nuclear/particle physics, astrophysics, and cosmology.