We report experiments on micron-scale normal metal loop connected by superconducting wires, where the sample geometry enables full modulation of the thermal activation barrier with applied magnetic flux, resembling a symmetric quantum interference device. We find that except a constant factor of five, the modulation of the barrier can be well fitted by the Ambegaokar-Halperin model for a resistively shunted junction, extended here to a proximity junction with flux-tunable coupling energy estimated using quasiclassical theory. This observation sheds light on the understanding of effect of thermal fluctuation in proximity junctions, while may also lead to an unprecedented level of control in quantum interference devices.