The density dependence of the nuclear symmetry energy is inspected using the Statistical Multifragmentation Model with Skyrme effective interactions. The model consistently considers the expansion of the fragments volumes at finite temperature at the freeze-out stage. By selecting parameterizations of the Skyrme force that lead to very different equations of state for the symmetry energy, we investigate the sensitivity of different observables to the properties of the effective forces. Our results suggest that, in spite of being sensitive to the thermal dilation of the fragments volumes, it is difficult to distinguish among the Skyrme forces from the isoscaling analysis. On the other hand, the isotopic distribution of the emitted fragments turns out to be very sensitive to the force employed in the calculation.