Recent experimental results demonstrated the generation of a quantum superpositon (MQS), involving a number of photons in excess of 5x10^4, which showed a high resilience to losses. In order to perform a complete analysis on the effects of de-coherence on this multiphoton fields, obtained through the Quantum Injected Optical Parametric Amplifier (QIOPA), we invesigate theoretically the evolution of the Wigner functions associated to these states in lossy conditions. Recognizing the presence of negative regions in the W-representation as an evidence of non-classicality, we focus our analysis on this feature. A close comparison with the MQS based on coherent states allows to identify differences and analogies.