We used a torsion pendulum containing $approx 10^{23}$ polarized electrons to search new interactions that couple to electron spin. We limit CP-violating interactions between the pendulums electrons and unpolarized matter in the earth or the sun, test for rotation and boost-dependent preferred-frame effects using the earths rotation and velocity with respect to the entire cosmos, and search for exotic velocity-dependent potentials between polarized electrons and unpolarized matter in the sun and moon. Finally, we find that the gravitational mass of an electron spinning toward the galactic center differs by less than about 1 part in $10^{21}$ from an electron spinning in the opposite direction. As a byproduct of this work, the density of polarized electrons in Sm$ $Co$_5$ was measured to be $(4.19pm 0.19)times 10^{22} {rm cm}^{-3}$ at a field of 9.6 kG.
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