We model the transport of cosmic ray nuclei in the Galaxy by means of a new numerical code. Differently from previous numerical models we account for a generic spatial distribution of the diffusion coefficient. We found that in the case of radially uniform diffusion, the main secondary/primary ratios (B/C, N/O and sub-Fe/Fe) and the modulated antiproton spectrum match consistently the available observations. Convection and re-acceleration do not seem to be required in the energy range we consider: $1 < E < 10^3$ GeV/nucleon. We generalize these results accounting for radial dependence of the diffusion coefficient, which is assumed to trace that of the cosmic ray sources. While this does not affect the prediction of secondary/primary ratios, the simulated longitude profile of the diffuse $gamma$-ray emission is significantly different from the uniform case and may agree with EGRET measurements without invoking ad hoc assumptions on the galactic gas density distribution.
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