In February 2007, the fourth stage of the Mainz Microtron, MAMI-C, started operations with a first experiment. The new Harmonic Double-Sided Microtron delivers an electron beam with energies up to 1.5 GeV while preserving the excellent beam quality of the previous stages. The experimental program at MAMI is focused on studies of the hadron structure in the domain of non-perturbative QCD. In this paper, a few prominent selections of the extensive physics program at MAMI-C will be presented.