Recently, observations of compact stars have provided new data of high accuracy which put strong constraints on the high-density behaviour of the equation of state of strongly interacting matter otherwise not accessible in terrestrial laboratories. The evidence for neutron stars with high mass (M =2.1 +/- 0.2 M_sun for PSR J0751+1807) and large radii (R > 12 km for RX J1856-3754) rules out soft equations of state and has provoked a debate whether the occurence of quark matter in compact stars can be excluded as well. In this contribution it is shown that modern quantum field theoretical approaches to quark matter including color superconductivity and a vector meanfield allow a microscopic description of hybrid stars which fulfill the new, strong constraints. The deconfinement transition in the resulting stiff hybrid equation of state is weakly first order so that signals of it have to be expected due to specific changes in transport properties governing the rotational and cooling evolution caused by the color superconductivity of quark matter. A similar conclusion holds for the investigation of quark deconfinement in future generations of nucleus-nucleus collision experiments at low temperatures and high baryon densities such as CBM @ FAIR.
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