MIDIR is the proposed thermal/mid-IR imager and spectrograph for the European Extremely Large Telescope (E-ELT). It will cover the wavelength range of 3 to at least 20 microns. Designed for diffraction-limited performance over the entire wavelength range, MIDIR will require an adaptive optics system; a cryogenically cooled system could offer optimal performance in the IR, and this is a critical aspect of the instrument design. We present here an overview of the project, including a discussion of MIDIRs science goals and a comparison with other infrared (IR) facilities planned in the next decade; top level requirements derived from these goals are outlined. We describe the optical and mechanical design work carried out in the context of a conceptual design study, and discuss some important issues to emerge from this work, related to the design, operation and calibration of the instrument. The impact of telescope optical design choices on the requirements for the MIDIR instrument is demonstrated.