Schroedingers book What is Life? is widely credited for having played a crucial role in development of molecular and cellular biology. My essay revisits the issues raised by this book from the modern perspective of epigenetics and systems biology. I contrast two classes of potential mechanisms of epigenetic stability: epigenetic templating and systems biology approaches, and consider them from the point of view expressed by Schroedinger. I also discuss how quantum entanglement, a nonclassical feature of quantum mechanics, can help to address the problem of small numbers that lead Schroedinger to promote the idea of molecular code-script for explanation of stability of biological order.
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