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In the context of a high-dimensional linear regression model, we propose the use of an empirical correlation-adaptive prior that makes use of information in the observed predictor variable matrix to adaptively address high collinearity, determining if parameters associated with correlated predictors should be shrunk together or kept apart. Under suitable conditions, we prove that this empirical Bayes posterior concentrates around the true sparse parameter at the optimal rate asymptotically. A simplified version of a shotgun stochastic search algorithm is employed to implement the variable selection procedure, and we show, via simulation experiments across different settings and a real-data application, the favorable performance of the proposed method compared to existing methods.
In high-dimensions, the prior tails can have a significant effect on both posterior computation and asymptotic concentration rates. To achieve optimal rates while keeping the posterior computations relatively simple, an empirical Bayes approach has r
For a multivariate linear model, Wilks likelihood ratio test (LRT) constitutes one of the cornerstone tools. However, the computation of its quantiles under the null or the alternative requires complex analytic approximations and more importantly, th
Labeling patients in electronic health records with respect to their statuses of having a disease or condition, i.e. case or control statuses, has increasingly relied on prediction models using high-dimensional variables derived from structured and u
Heterogeneity is an important feature of modern data sets and a central task is to extract information from large-scale and heterogeneous data. In this paper, we consider multiple high-dimensional linear models and adopt the definition of maximin eff
Inferring causal relationships or related associations from observational data can be invalidated by the existence of hidden confounding. We focus on a high-dimensional linear regression setting, where the measured covariates are affected by hidden c