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Reconstruction Algorithm Design for Mitigating the Orientation Dependent Conspicuity of Fiber-Like signals in Digital Breast Tomosynthesis

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 نشر من قبل Sean Rose
 تاريخ النشر 2018
  مجال البحث فيزياء
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There are a number of clinically relevant tasks in digital breast tomosynthesis (DBT) involving the detection and visual assessment of fiber-like structures such as Coopers ligaments, blood vessels, and spiculated lesions. Such structures can exhibit orientation dependent variations in conspicuity. This study demonstrates the presence of in-plane orientation-dependent signal conspicuity for fiber-like signals in DBT and shows how reconstruction algorithm design can mitigate this phenomenon. We uncover a tradeoff between minimizing orientation-dependence and preserving depth resolution that is dictated by the regularization strength employed in reconstruction.



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