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The early star-forming Universe is still poorly constrained, with the properties of high-redshift stars, the first heating sources, and reionization highly uncertain. This leaves observers planning 21-cm experiments with little theoretical guidance. In this work we explore the possible range of high-redshift parameters including the star formation efficiency and the minimal mass of star-forming halos; the efficiency, spectral energy distribution, and redshift evolution of the first X-ray sources; and the history of reionization. These parameters are only weakly constrained by available observations, mainly the optical depth to the cosmic microwave background. We use realistic semi-numerical simulations to produce the global 21-cm signal over the redshift range $z = 6-40$ for each of 193 different combinations of the astrophysical parameters spanning the allowed range. We show that the expected signal fills a large parameter space, but with a fixed general shape for the global 21-cm curve. Even with our wide selection of models we still find clear correlations between the key features of the global 21-cm signal and underlying astrophysical properties of the high redshift Universe, namely the Ly$alpha$ intensity, the X-ray heating rate, and the production rate of ionizing photons. These correlations can be used to directly link future measurements of the global 21-cm signal to astrophysical quantities in a mostly model-independent way. We identify additional correlations that can be used as consistency checks.
The high-redshift 21-cm signal of neutral hydrogen is expected to be observed within the next decade and will reveal epochs of cosmic evolution that have been previously inaccessible. Due to the lack of observations, many of the astrophysical process
One approach to extracting the global 21-cm signal from total-power measurements at low radio frequencies is to parametrize the different contributions to the data and then fit for these parameters. We examine parametrizations of the 21-cm signal its
The 21-cm signal of neutral hydrogen is a sensitive probe of the Epoch of Reionization (EoR) and Cosmic Dawn. Currently operating radio telescopes have ushered in a data-driven era of 21-cm cosmology, providing the first constraints on the astrophysi
The 21-cm signal from the Cosmic Dawn (CD) is likely to contain large fluctuations, with the most extreme astrophysical models on the verge of being ruled out by observations from radio interferometers. It is therefore vital that we understand not on
The motion of the solar system with respect to the cosmic rest frame modulates the monopole of the Epoch of Reionization 21-cm signal into a dipole. This dipole has a characteristic frequency dependence that is dominated by the frequency derivative o