Unsupervised Machine Translation (MT) model, which has the ability to perform MT without parallel sentences using comparable corpora, is becoming a promising approach for developing MT in low-resource languages. However, majority of the studies in unsupervised MT have considered resource-rich language pairs with similar linguistic characteristics. In this paper, we investigate the effectiveness of unsupervised MT models over a Manipuri-English comparable corpus. Manipuri is a low-resource language having different linguistic characteristics from that of English. This paper focuses on identifying challenges in building unsupervised MT models over the comparable corpus. From various experimental observations, it is evident that the development of MT over comparable corpus using unsupervised methods is feasible. Further, the paper also identifies future directions of developing effective MT for Manipuri-English language pair under unsupervised scenarios.